YENCHEN MACHINERY CO., LTD. - Yenchen Machinery - leading pharmaceutical machinery manufacture in Taiwan

FAQs | Black Spots on Tablets, Grey Smudges | Manufacturing Equipment for Pharmaceutical Industry | Yenchen

Yenchen is a high-quality Solid Dosage Line, Pellet Machine Production Line, Syrup Line, Injection Line, Ointment Line, Extraction & Concentration Turn Key Equipments supplier from Taiwan since 1967. Yenchen was established in 1967, our products and services are widely used in the pharmaceutical, food, biotechnology, chemical, and cosmetic fields, which include solid dosage line, pellet machine production line, syrup line, injection line, ointment line, extraction & concentration turnkey equipments.

Black Spots on Tablets, Grey Smudges | Tablet & Sterilization Machines - Pharmaceutical Manufacturing Equipment | Yenchen

Black Spots on Tablets, Grey Smudges | Yenchen Machinery Co., Ltd. has been specializing in manufacturing Pharmaceutical Machine for 60 years.

Black Spots on Tablets, Grey Smudges

Black Spots on Tablets, Grey Smudges

Source : Yenchen Technical Process Consultant, Dr. Fred Rowley

Problem:
  • Colored spots in the coating on the tablets. (usually grey, sometimes black, sometimes unusual color).
  • Not every tablet will have the defect; only those that receive a sharp, hard particle of Titanium oriented so as to initiate a rub or that have a particle of zinc stearate on the surface of the tablet.
Root Causes:
  • High content of titanium dioxide in the coating material.
  • Zinc stearate in the formula.
  • Iron oxides trapped in the coating pan.
  • No passivation performed
  • Interaction of factors.
Important note:

This can be a highly complex problem involving titanium dioxide, zinc stearate, stainless steel and iron oxides.


If you have any technical questions, please contact with Grace Chiang Email:grace.chiang@yenchen.com.tw
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Black Spots on Tablets, Grey Smudges | Tablet & Sterilization Machines - Pharmaceutical Manufacturing Equipment | Yenchen

Located in Taiwan since 1967, YENCHEN MACHINERY CO., LTD. has been a pharmaceutical manufacturing equipment supplier in pharmaceutical industry. Their main manufacturing and processing equipment include, hot air sterilizers, extrusion machines, tablet coating and compression machines, pellet making machines and oral solid dosage manufacturing equipment, which are sold to over 70 countries meeting international standards.

Yenchen was established in 1967, our products and services are widely used in the pharmaceutical, food, biotechnology, chemical, and cosmetic fields, which include solid dosage line, pellet machine production line, syrup line, injection line, ointment line, extraction & concentration turnkey equipments.

Yenchen has been offering customers high-quality pharmaceutical manufacturing equipment since 1967, both with advanced technology and 57 years of experience, Yenchen ensures each customer's demands are met.