Final Blending and Blend Lubrication | Tablet & Sterilization Machines - Pharmaceutical Manufacturing Equipment | Yenchen

blending | Yenchen Machinery Co., Ltd. has been specializing in manufacturing Pharmaceutical Machine for 60 years.

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Final Blending and Blend Lubrication

Source : Yenchen Technical Process Consultant, Dr. Fred Rowley


1. Perfect Content and Perfect Lubrication

Stop blender, add the mag stearate

Blue dots represent 8 samples pulled at 8 locations in a twin shell blender holding 1000kg at 8 rpm at 60% occupancy

2. Bad Content Uniformity and Perfect Lubrication

Stop blender, add the mag stearate

3. Acceptable content at 1 min lube time with perfect content/over-lubricated at 5 min lube time

Stop blender, add the mag stearate

3a. Perfect content and over lubrication at 15 min lube time with an additional dissolution failure

Mag stearate added with all the other components

4. Bad Content Uniformity and Over-Lubricated at 8 minutes

Stop blender, add the mag stearate

5. Perfect Content Uniformity and Under (variable) Lubrication at 10 seconds. Perfect Content and Lubrication at 2minutes

Stop blender, add the mag stearate

Perfect content uniformity. Some tablets are over lubricated and are therefore soft and have lamination while other tablets are harder and exhibit no lamination.

6. Bad Content Uniformity and Variable (Under) Lubrication

Stop blender, add the mag stearate




If you have any technical questions, please contact with Grace Chiang Email:grace.chiang@yenchen.com.tw
Copyright © 2019 YENCHEN MACHINERY CO., LTD. All Rights Reserved.

Final Blending and Blend Lubrication | Tablet & Sterilization Machines - Pharmaceutical Manufacturing Equipment | Yenchen

Located in Taiwan since 1967, YENCHEN MACHINERY CO., LTD. has been a pharmaceutical manufacturing equipment supplier in pharmaceutical industry. Their main manufacturing and processing equipment include, hot air sterilizers, extrusion machines, tablet coating and compression machines, pellet making machines and oral solid dosage manufacturing equipment, which are sold to over 70 countries meeting international standards.

Yenchen was established in 1967, our products and services are widely used in the pharmaceutical, food, biotechnology, chemical, and cosmetic fields, which include solid dosage line, pellet machine production line, syrup line, injection line, ointment line, extraction & concentration turnkey equipments.

Yenchen has been offering customers high-quality pharmaceutical manufacturing equipment since 1967, both with advanced technology and 57 years of experience, Yenchen ensures each customer's demands are met.