YENCHEN MACHINERY CO., LTD. - Yenchen Machinery - leading pharmaceutical machinery manufacture in Taiwan

FAQs | Understanding Scale Up of The Tablet Compaction -1 | Manufacturing Equipment for Pharmaceutical Industry | Yenchen

Yenchen is a high-quality Solid Dosage Line, Pellet Machine Production Line, Syrup Line, Injection Line, Ointment Line, Extraction & Concentration Turn Key Equipments supplier from Taiwan since 1967. Yenchen was established in 1967, our products and services are widely used in the pharmaceutical, food, biotechnology, chemical, and cosmetic fields, which include solid dosage line, pellet machine production line, syrup line, injection line, ointment line, extraction & concentration turnkey equipments.

Understanding Scale Up of The Tablet Compaction -1 | Tablet & Sterilization Machines - Pharmaceutical Manufacturing Equipment | Yenchen

Tablet Presses | Yenchen Machinery Co., Ltd. has been specializing in manufacturing Pharmaceutical Machine for 60 years.

Tablet Presses

Understanding Scale Up of The Tablet Compaction -1

Source : Yenchen Technical Process Consultant, Dr. Fred Rowley

Operation The Controls on All Modern Tablet Presses:

1. Fill volume: weight


Die Volume = Tablet Weight = Content Uniformity
  • The press does not weigh powder, it fills by volume.
  • Particle size and density are the key factors for good weight control.
  • Scrape off is critical.
Volume = Weight

2. Pre-compression thickness


Adjust Pre-Compression: Thickness and Upper Punch Entry Controls
  • During tablet compression entrapped air has only two places to go:
    - Out of the die.
    - Into the tablet.
  • We have the pre compression and upper punch entry controls to minimize air entrapment.
Pre-compression thickness

3. Main or final thickness


Adjusting Pre-Compression Thickness
  • Objective: drive the air out of the powder.
  • Suggested setting: 1.5 to 3.0 times the final target for tablet thickness.
  • Similar to 4 wheel drive: sometimes you need it, other times you do not.
  • If not needed, back the control off all the way.
Main or final thickness



If you have any technical questions, please contact with Grace Chiang Email:grace.chiang@yenchen.com.tw
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Understanding Scale Up of The Tablet Compaction -1 | Tablet & Sterilization Machines - Pharmaceutical Manufacturing Equipment | Yenchen

Located in Taiwan since 1967, YENCHEN MACHINERY CO., LTD. has been a pharmaceutical manufacturing equipment supplier in pharmaceutical industry. Their main manufacturing and processing equipment include, hot air sterilizers, extrusion machines, tablet coating and compression machines, pellet making machines and oral solid dosage manufacturing equipment, which are sold to over 70 countries meeting international standards.

Yenchen was established in 1967, our products and services are widely used in the pharmaceutical, food, biotechnology, chemical, and cosmetic fields, which include solid dosage line, pellet machine production line, syrup line, injection line, ointment line, extraction & concentration turnkey equipments.

Yenchen has been offering customers high-quality pharmaceutical manufacturing equipment since 1967, both with advanced technology and 57 years of experience, Yenchen ensures each customer's demands are met.