
Cleaning Validation
Source : Yenchen Technical Process Consultant, Dr. Fred Rowley
Key Question
1. At what point does a piece of equipment or system become clean? Does it have to be scrubbed by hand?
2. What is accomplished by hand scrubbing rather than just a solvent wash?
3. How variable are manual cleaning processes from batch to batch and product to product?
Cleanig Methods
- Physical removal
 - Solubility based cleaning
 - Wetting
 - Emulsification
 - Dispersion
 - Oxidation
 - Hydrolysis
 - Antimicrobial action
 
If you have any technical questions, please contact with Grace Chiang Email:grace.chiang@yenchen.com.tw
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