YENCHEN MACHINERY CO., LTD. - Yenchen Machinery - leading pharmaceutical machinery manufacture in Taiwan

FAQs | Understanding The Keys to MUPS Tablet Compressing Success | Manufacturing Equipment for Pharmaceutical Industry | Yenchen

Yenchen is a high-quality Solid Dosage Line, Pellet Machine Production Line, Syrup Line, Injection Line, Ointment Line, Extraction & Concentration Turn Key Equipments supplier from Taiwan since 1967. Yenchen was established in 1967, our products and services are widely used in the pharmaceutical, food, biotechnology, chemical, and cosmetic fields, which include solid dosage line, pellet machine production line, syrup line, injection line, ointment line, extraction & concentration turnkey equipments.

Understanding The Keys to MUPS Tablet Compressing Success | Tablet & Sterilization Machines - Pharmaceutical Manufacturing Equipment | Yenchen

Understanding The Keys to MUPS Tablet Compressing Success | Yenchen Machinery Co., Ltd. has been specializing in manufacturing Pharmaceutical Machine for 60 years.

Understanding The Keys to MUPS Tablet Compressing Success

Understanding The Keys to MUPS Tablet Compressing Success

Source : Yenchen Technical Process Consultant, Dr. Fred Rowley

Overview:

  • The beads are manufactured in a fluid air bed system.
  • Sugar spheres in suspension are sequentially sprayed with aqueous suspensions of a drug, a protective layer, an enteric coating and an outer layer to reduce granule aggregation.
  • The beads are mixed with other excipients and compressed into tablets.
  • The tablets are sometimes film-coated to improve the stability and appearance of preparation.
  • Essentially, the tablet consists of extremely small enteric-coated beads of the active pharmaceutical ingredient inside an outer shell.
  • When the tablet is immersed in an aqueous solution, as happens when the tablet reaches the stomach, water enters the tablet by osmosis. The contents swell from water absorption causing the shell to burst, releasing the enteric-coated granules.

Understanding The Keys to Compressing Success

  • A. Storage and Handling
  • B. Head pressure and valve settings
  • C. Hopper geometry and Feeder charge
  • D. Optimized fill cam selection
  • E. Feeder charge and wheel speeds
  • F. Powder recirculation
  • G. The concept of the double hit
  • H. Press start up and tablet compressing
       - Start up
       - Steady state operation
       - End of run



If you have any technical questions, please contact with Grace Chiang Email:grace.chiang@yenchen.com.tw
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Understanding The Keys to MUPS Tablet Compressing Success | Tablet & Sterilization Machines - Pharmaceutical Manufacturing Equipment | Yenchen

Located in Taiwan since 1967, YENCHEN MACHINERY CO., LTD. has been a pharmaceutical manufacturing equipment supplier in pharmaceutical industry. Their main manufacturing and processing equipment include, hot air sterilizers, extrusion machines, tablet coating and compression machines, pellet making machines and oral solid dosage manufacturing equipment, which are sold to over 70 countries meeting international standards.

Yenchen was established in 1967, our products and services are widely used in the pharmaceutical, food, biotechnology, chemical, and cosmetic fields, which include solid dosage line, pellet machine production line, syrup line, injection line, ointment line, extraction & concentration turnkey equipments.

Yenchen has been offering customers high-quality pharmaceutical manufacturing equipment since 1967, both with advanced technology and 57 years of experience, Yenchen ensures each customer's demands are met.