Fluid Bed Dryer, Granulator, Coater
Principles:1. Top Spray Gruanlation
Spray atomized binder or active ingredients from the top onto the fluidized powder to form the even granules.
2. Bottom Spray Coating
When the hot air passes through the bottom plate of container and partition column, it will generate the siphon effect. The pellets will fall down and then sucked back to the partition column again, while the bottom spray gun will spray coating binder upward to achieve coating purpose.
3. Side Spray Powder Coating/Film Coating
The side spray is better for caoting with high firm content. The cores (seeds) are placed on the turntable disc and hot air is blown upward between the turntable disc and the granulation area. The coating solution is sprayed on the rolling cores through the pump and spray gun. The process involves simultaneous coating and drying of the cores, the repeated actions achieve the desired coating thickness or granule size. Powder coating is achieved by charging powder and spray binder at the same time.
1. Comply with regulations of cGMP, PIC/S GMP, FDA.
2. Bag filter shaking mode: double shaking. (or air purge type)
3. Contact material: SUS316L, inner polishing surface Ra <0.4.
4. Sample taking by sampling vial, for ease of sampling.
5. The material of bag filter is made of polyester fibers and stainless steel fibers with anti-static electricity conductivity cloth. Bag filter lifting by auto pneumatic cylinder.
6. Air inlet system equipped with pre-filter, mid filter, and HEPA 99.97% 0.3μ to ensure the cleanness of inlet air.
7. Critical parameter graph controlling: temperature, humidity, air flow, spray volume, etc.
8. Top spray: adopted SCHLICK modular single-head spray gun, even spray pattern and fast granulation.
9. Multi-purposes: one machine can perform multiple functions, drying, granulation, powder coating, pellet film coating, pellet enteric coating.
10. Two sets of valves are interacting automatically to fluidize the granules continuously.
|Bottom spray capacity|
|Side spray capacity|
- Top Spray:
Pharmaceutical: For medicines, biopharmaceutical, and Chinese medicine’s granulation or drying.
Food: Instant food, juice powder, seasoning, food additive, lactic acid bacteria’s granulation or drying.
- Bottom & Side Spray: Medicines and healthy food for a controlled release of active ingredients.
- PLC+HMI control
- Conform to 21CFR Part11
- User authorization level: 3~4 levels
- Recipes and production batch records storage is available.
- Critical parameter graph: temperature, humidity, air flow, solution spray volume, pressure difference etc.
- Components of control system: well-known global brands. Air unit: FESTO
Complete documents and test could be provided
- Qualification document: includes DQ/IQ/OQ/FAT/SAT
- Testing instruments are available at site: elemental analyzer, surface roughness measurement, velocity meter, etc.
- FAT: all utility sources are ready at site, such as steam, chilling water and compressed air. Sample trial run can be executed.
- Explosion proof system (for organic solvent)
i. 2 bar pressure resistant design: Suitable for the rooms on the top floor (Safety relief ducting upward)
ii. 2 bar pressure resistant design: Suitable rooms at the corner (Safety relief ducting backward)
iii. 10 bar pressure resistant design: No safety relief duct
(YENCHEN is the first Asian company certificated by ATEX for the fluid bed dryer granulator.)
- WIP or CIP system
- Donaldson dry dust collector system
- Auto air volume control and display
- Solution flow rate control: load cell/liquid flow meter
- Powder leakage detector
- Suction system (connect to YENCHEN's Super Mixer / Granulator)
- Closed type discharge lifting and tilting device
- Related Products
Drying: The high drying efficiency is because the powder or granules are fluidized in the drying chamber and the container is using a turbo blower, the hot air passed through the powder or granules from bottom to the top of drying chamber to remove the humidity.Granulation: Spray atomized binder or active ingredients on the suspension powder by spray guns to formm the uniformity granules.
Yenchen Machinery Co., Ltd has an excellent reputation for product and services in the world, including tablet process line, controlled-release pellets equipment, automatic extraction and concentration equipment, oral dosage equipment, injection equipment, ointment equipment. The total solution and customized services for pharmaceutical, food, biotechnology, chemical engineering, and cosmetics industries makes Yenchen the leading biotech pharmaceutical equipment suppliers in Taiwan.Yenchen successfully developed YC-FBAS-1200, continuous fluid bed dryer ,working capacity 700 ~ 720Kg / hr. In the use of high-pressure blower, let powder or granules floating in the drying chamber, hot air from the bottom up through, sufficient and uniform 360∘ contacting the powder or granules, the water evaporation, so the drying efficiency is particularly good. Unique modular design makes the product system can be equipped with different dehumidifier, heater, and automatic control function modules, to fully meet the different requirement of each user.Design of this machine can reduce risk of contamination in the transportation, save labor and the drying time. It is easy to operate according to the SOP without specialized technical personnel. And it is easy to clean, easy to maintain. Due to the superior functionality allows users to reduce manufacturing costs. All contact materials are made of non-reactive, non-decomposable 316L stainless steel, and use of Teflon or Silicon packing. All welded personnel have valid license, and the machine will proceed inspection, polishing, pickling, and cleaning procedures before delivery.Yenchen adhere the core values of innovative research and development, combined with multiple resources of industry, government and scholarship, to develop new products to meet the requirement of the industry, expand to the feed market.
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Over 50 Years Fluid Bed Dryer, Granulator, Coater | Pharmaceutical Processing Equipment | Yenchen
Based in Taiwan, YENCHEN MACHINERY CO., LTD., since 1967, is a Fluid Bed Dryer, Granulator, Coater | pharmaceutical processing machinery supplier. Pharmaceutical production lines used in the pharma, food, biotechnology, chemical, and cosmetic fields, which include solid dosage line, pellet machine production line, syrup line, injection line, ointment line, extraction & concentration turn key equipment.
Worldwide sales references in over 70 countries, 6000 square meter production factory allows high-quality pharmaceutical equipment supplies. Hundreds of similar companies have been enjoying our pellet & pharmaceutical processing machinery and services for years.
Yenchen has been offering customers high-quality pharmaceutical equipment since 1967, both with advanced technology and 54 years of experience, Yenchen ensures each customer's demands are met.